Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | FAAH | O00519 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.41 |
| ▸ | PTAFR | P25105 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6952538 | 0.92 | FAAH (0.44) | NLRP3MAPTCYP3A4FAAHPTAFR | |
| SCHEMBL6949829 | 0.90 | FAAH (0.41) | NLRP3MAPTCYP3A4FAAHPOLB | |
| SCHEMBL6358943 | 0.90 | FOLH1 (0.48) | MAPTCYP3A4FAAHPTAFR | |
| SCHEMBL6954777 | 0.89 | FOLH1 (0.47) | MAPTCYP3A4FAAHPTAFR | |
| SCHEMBL7393082 | 0.78 | FLT4 (0.46) | NLRP3CYP3A4FAAHPOLBPTAFR | |
| SCHEMBL4924109 | 0.77 | ITGB3 (0.52) | PTAFR | |
| SCHEMBL6947579 | 0.76 | ITGB3 (0.51) | MAPTCYP3A4PTAFRHDAC6 | |
| SCHEMBL8496788 | 0.76 | CYP3A4 (0.64) | MAPTCYP3A4FAAHPOLBPTAFR | |
| SCHEMBL6950532 | 0.75 | L3MBTL1 (0.41) | NLRP3CYP3A4 | |
| SCHEMBL6358935 | 0.75 | FOLH1 (0.49) | MAPTCYP3A4FAAHPTAFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0804418-B1 | PLATELET AGGREGATION INHIBITORS | SEARLE & CO (US) | 2003-03-26 | — | — | EP | claimed |
| US-5639765-A | OSTEOPOROSIS, PAGET*S DISEASE | G. D. SEARLE & CO. (US) | 1997-06-17 | — | — | US | claimed |
| US-5602155-A | GUANIDINO ALKYL AND PYRIDINE CARBOXYLATE SUBSTITUTED AMIDES | G. D. SEARLE & CO. (US) | 1997-02-11 | — | — | US | claimed |
| WO-1996023771-A2 | PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1996-08-08 | — | — | WO | claimed |
| EP-0804418-B1 | PLATELET AGGREGATION INHIBITORS | SEARLE & CO (US) | 2003-03-26 | — | — | EP | disclosed |
| US-5639765-A | OSTEOPOROSIS, PAGET*S DISEASE | G. D. SEARLE & CO. (US) | 1997-06-17 | — | — | US | disclosed |
| US-5602155-A | GUANIDINO ALKYL AND PYRIDINE CARBOXYLATE SUBSTITUTED AMIDES | G. D. SEARLE & CO. (US) | 1997-02-11 | — | — | US | disclosed |
| WO-1996023771-A2 | PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1996-08-08 | — | — | WO | disclosed |