Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 5/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | KIT | P10721 | 1/20 | 0.34 |
| ▸ | ATR | Q13535 | 1/20 | 0.33 |
| ▸ | GRM1 | Q13255 | 7/20 | 0.32 |
| ▸ | GRM5 | P41594 | 6/20 | 0.32 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.32 |
| ▸ | WNT3A | P56704 | 1/20 | 0.32 |
| ▸ | CDK7 | P50613 | 1/20 | 0.32 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.32 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6953065 | 0.86 | CYP11B2 (0.36) | NAMPTCYP11B2BTKKITGRM1 | |
| SCHEMBL6041476 | 0.83 | NAMPT (0.53) | NAMPTCYP11B2BTKATRGRM1 | |
| SCHEMBL6957185 | 0.79 | PPARG (0.44) | NAMPTPPARGPPARA | |
| SCHEMBL6953745 | 0.79 | GRM5 (0.44) | NAMPTGRM1GRM5 | |
| SCHEMBL6955999 | 0.77 | S1PR1 (0.42) | NAMPTBTKGRM1GRM5WNT3A | |
| SCHEMBL19514111 | 0.76 | GPR119 (0.42) | NAMPTBTKPPARGPPARA | |
| SCHEMBL7080902 | 0.75 | S1PR1 (0.37) | NAMPTBTKGRM1GRM5PPARG | |
| SCHEMBL6956650 | 0.73 | S1PR1 (0.40) | NAMPTBTKGRM1GRM5PPARG | |
| SCHEMBL6954561 | 0.73 | GRM5 (0.49) | GRM1GRM5PDK4PPARGPPARA | |
| SCHEMBL27944985 | 0.73 | NAMPT (0.40) | NAMPTCYP11B2BTKATRPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863875-B1 | NEW 4-(OXYALKOXYPHENYL)-3-OXY-PIPERIDINES FOR TREATING HEART AND KIDNEY INSUFFICIENCY | HOFFMANN LA ROCHE (CH) | 2003-06-04 | — | — | EP | disclosed |