Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | GNRHR | P30968 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 3/20 | 0.34 |
| ▸ | SETDB1 | Q15047 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | XIAP | P98170 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6972880 | 0.86 | POLB (0.43) | RAB9AMEN1KMT2A | |
| SCHEMBL6964459 | 0.75 | IDH1 (0.37) | SLC6A4 | |
| SCHEMBL6957643 | 0.67 | MEP1A (0.42) | P2RX7 | |
| SCHEMBL6972391 | 0.67 | MEP1A (0.39) | SLC6A4 | |
| SCHEMBL6970716 | 0.67 | F11 (0.39) | MEN1KMT2ASLC6A4 | |
| SCHEMBL6967559 | 0.66 | PDK1 (0.39) | MEN1KMT2ASLC6A4 | |
| SCHEMBL6960685 | 0.66 | MEP1A (0.38) | MEN1KMT2ASLC6A4 | |
| SCHEMBL931667 | 0.63 | SLC6A4 (0.50) | OPRM1OPRL1MEN1KMT2ASLC6A4 | |
| SCHEMBL5099691 | 0.62 | HSD17B10 (0.62) | MEN1KMT2ASLC6A4 | |
| SCHEMBL15687214 | 0.62 | ADORA2A (0.38) | SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |