Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 8/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 8/20 | 0.36 |
| ▸ | EED | O75530 | 2/20 | 0.35 |
| ▸ | SUZ12 | Q15022 | 2/20 | 0.35 |
| ▸ | EZH2 | Q15910 | 2/20 | 0.35 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6956175 | 0.82 | MTNR1B (0.37) | MTNR1BMTNR1ASLC9A1TSHRMAP3K14 | |
| SCHEMBL6955724 | 0.82 | EED (0.42) | EEDSUZ12EZH2 | |
| SCHEMBL6949055 | 0.79 | HTR2C (0.35) | MTNR1BEEDSUZ12EZH2 | |
| Hydrochloric Acid SCHEMBL6948371 | 0.78 | HTR2C (0.35) | MTNR1BEEDSUZ12EZH2 | |
| SCHEMBL6950270 | 0.76 | MTNR1B (0.56) | MTNR1BMTNR1A | |
| SCHEMBL6948957 | 0.75 | MTNR1A (0.48) | MTNR1BMTNR1ASLC9A1SLC9A5SLC9A2 | |
| SCHEMBL126247 | 0.72 | DRD2 (0.37) | MTNR1BMTNR1ASLC9A1MAP3K14 | |
| SCHEMBL20744138 | 0.69 | HTR2C (0.35) | MTNR1BSLC9A1 | |
| SCHEMBL30754266 | 0.69 | MTNR1B (0.35) | MTNR1BMTNR1AHDAC3HDAC4HDAC1 | |
| SCHEMBL1764937 | 0.69 | MTNR1B (0.35) | MTNR1BMTNR1AHDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0901483-B1 | BENZOFURANS AND BENZOPYRANS AS CHRONOBIOLOGICAL AGENTS | GLAXO GROUP LTD (GB) | 2003-07-09 | — | — | EP | disclosed |
| US-5981572-A | Benzofurans and benzopyrans as chronobiological agents | GLAXO WELLCOME INC. (US) | 1999-11-09 | — | — | US | disclosed |