Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.47 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.45 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.45 |
| ▸ | OXTR | P30559 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6970758 | 0.86 | ALDH1A1 (0.45) | STAT3AVPR2AVPR1AOXTRHSD17B10 | |
| SCHEMBL6960033 | 0.79 | AVPR2 (0.53) | AVPR2AVPR1AOXTRNAMPT | |
| SCHEMBL22539212 | 0.75 | XIAP (0.59) | AVPR2AVPR1APOLBLMNAALDH1A1 | |
| SCHEMBL6967260 | 0.74 | AVPR2 (0.48) | AVPR2AVPR1ALMNATSHRMEN1 | |
| SCHEMBL6970673 | 0.74 | AVPR2 (0.48) | AVPR2AVPR1AOXTRPOLBLMNA | |
| SCHEMBL6960127 | 0.73 | NPSR1 (0.49) | AVPR2AVPR1APOLBLMNAHTT | |
| SCHEMBL6969600 | 0.73 | AVPR2 (0.46) | AVPR2AVPR1AHSD17B10LMNATSHR | |
| SCHEMBL6964588 | 0.73 | AVPR2 (0.46) | AVPR2AVPR1AHSD17B10L3MBTL1HDAC1 | |
| SCHEMBL6972107 | 0.71 | NOTUM (0.46) | AVPR2AVPR1AOXTRPOLBLMNA | |
| SCHEMBL40506 | 0.70 | LMNA (0.61) | HSD17B10LMNACYP11B2MAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620216-B1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-01-08 | — | — | EP | disclosed |
| US-5521170-A | VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0620216-A1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |