Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.41 |
| ▸ | OXTR | P30559 | 1/20 | 0.41 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | NAMPT | P43490 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6955289 | 0.86 | STAT3 (0.47) | ALDH1A1MAPTSTAT3AVPR2OXTR | |
| SCHEMBL7140109 | 0.77 | L3MBTL1 (0.45) | ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL6955542 | 0.77 | ALDH1A1 (0.43) | ALDH1A1MAPTHTTL3MBTL1 | |
| SCHEMBL6971119 | 0.76 | DRD2 (0.46) | ALDH1A1MAPTHTTL3MBTL1 | |
| SCHEMBL6960033 | 0.76 | AVPR2 (0.53) | AVPR2OXTRAVPR1ANAMPT | |
| SCHEMBL6955643 | 0.75 | L3MBTL1 (0.46) | ALDH1A1POLBL3MBTL1 | |
| SCHEMBL6960079 | 0.75 | ALDH1A1 (0.48) | ALDH1A1L3MBTL1 | |
| SCHEMBL6958687 | 0.75 | DRD3 (0.46) | ALDH1A1MAPTAVPR2HTTHTR2C | |
| SCHEMBL6969126 | 0.74 | L3MBTL1 (0.45) | ALDH1A1MAPTPOLBL3MBTL1 | |
| SCHEMBL6969761 | 0.72 | L3MBTL1 (0.43) | ALDH1A1MAPTPOLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620216-B1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-01-08 | — | — | EP | disclosed |
| US-5521170-A | VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0620216-A1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |