Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6958441 | 0.82 | TP53 (0.36) | NAAATP53MAPTLMNAALDH1A1 | |
| SCHEMBL6964256 | 0.77 | TP53 (0.40) | TP53MAPTLMNAALDH1A1 | |
| SCHEMBL27398082 | 0.71 | LMNA (0.34) | NAAALMNACYP2C9 | |
| SCHEMBL9257560 | 0.70 | TP53 (0.48) | TP53MAPTLMNAALDH1A1 | |
| SCHEMBL675612 | 0.68 | NAAA (0.64) | NAAA | |
| SCHEMBL7827151 | 0.68 | TP53 (0.36) | TP53MAPTALDH1A1 | |
| SCHEMBL18656059 | 0.67 | LMNA (0.38) | TP53LMNACYP2C9ALDH1A1 | |
| SCHEMBL7694428 | 0.66 | NAAA (0.51) | NAAAMAPTLMNA | |
| SCHEMBL10337326 | 0.65 | NAAA (0.54) | NAAA | |
| SCHEMBL6966024 | 0.64 | POLB (0.33) | TP53MAPTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0974582-B1 | Process for the preparation of 4-substituted azetidinone derivatives | TAKASAGO PERFUMERY CO LTD (JP) | 2003-02-12 | — | — | EP | disclosed |
| US-6340751-B1 | REACTION OF IMIDAZOLONE WITH AMIDE AND MAGNESIUM COMPOUND | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2002-01-22 | — | — | US | disclosed |
| EP-0974582-A1 | Process for the preparation of 4-substituted azetidinone derivatives | Takasago International Corporation (JP) | 2000-01-26 | — | — | EP | disclosed |