Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6964256 | 0.79 | TP53 (0.40) | POLBALDH1A1LMNAOPRM1TP53 | |
| SCHEMBL6959688 | 0.75 | POLB (0.31) | POLBALDH1A1LMNA | |
| SCHEMBL10945424 | 0.65 | CYP19A1 (0.34) | — | |
| SCHEMBL2377717 | 0.65 | POLB (0.50) | POLBALDH1A1LMNA | |
| SCHEMBL6955467 | 0.64 | NAAA (0.37) | ALDH1A1LMNATP53MAPT | |
| SCHEMBL926627 | 0.64 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL6958441 | 0.63 | TP53 (0.36) | ALDH1A1LMNATP53MAPT | |
| SCHEMBL6535205 | 0.62 | CYP19A1 (0.30) | — | |
| SCHEMBL8779653 | 0.62 | L3MBTL1 (0.38) | POLBALDH1A1LMNAMAPT | |
| SCHEMBL23201305 | 0.62 | FFAR3 (0.34) | POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6340751-B1 | REACTION OF IMIDAZOLONE WITH AMIDE AND MAGNESIUM COMPOUND | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2002-01-22 | — | — | US | claimed |
| EP-0974582-B1 | Process for the preparation of 4-substituted azetidinone derivatives | TAKASAGO PERFUMERY CO LTD (JP) | 2003-02-12 | — | — | EP | disclosed |
| US-6340751-B1 | REACTION OF IMIDAZOLONE WITH AMIDE AND MAGNESIUM COMPOUND | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2002-01-22 | — | — | US | disclosed |
| EP-0974582-A1 | Process for the preparation of 4-substituted azetidinone derivatives | Takasago International Corporation (JP) | 2000-01-26 | — | — | EP | disclosed |