Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 4/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 2/20 | 0.34 |
| ▸ | HTR6 | P50406 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6955705 | 0.89 | KMT2A (0.43) | DRD2GAAKMT2AKDM4EMAPT | |
| Oxalic Acid SCHEMBL6965697 | 0.81 | OPRK1 (0.41) | DRD4GAAKMT2AKDM4EMAPT | |
| SCHEMBL6960765 | 0.77 | HRH1 (0.42) | DRD2DRD4DRD3KMT2AKDM4E | |
| SCHEMBL6965928 | 0.71 | DRD2 (0.59) | DRD2DRD4DRD3 | |
| Hydrochloric Acid SCHEMBL6972143 | 0.70 | DRD2 (0.58) | DRD2DRD4DRD3 | |
| SCHEMBL6973725 | 0.69 | HRH1 (0.47) | DRD2DRD3HTR1AHTR7HTR6 | |
| Hydrochloric Acid SCHEMBL8787544 | 0.67 | DRD2 (0.49) | DRD2DRD4DRD3HTR1AHTR2A | |
| SCHEMBL6716119 | 0.66 | GAA (0.49) | GAAKMT2AKDM4EMAPTCYP2C19 | |
| SCHEMBL8715531 | 0.65 | HTR2C (0.44) | DRD3HTR1ALMNA | |
| SCHEMBL6955492 | 0.65 | DRD2 (0.54) | DRD2DRD4DRD3KMT2AHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934312-B1 | 1,4-DISUBSTITUTED PIPERAZINES | NOVO NORDISK AS (DK) | 2003-03-19 | — | — | EP | claimed |