Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 9/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.42 |
| ▸ | DRD2 | P14416 | 3/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.42 |
| ▸ | HTR2A | P28223 | 3/20 | 0.42 |
| ▸ | HTR2C | P28335 | 3/20 | 0.42 |
| ▸ | DRD3 | P35462 | 3/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.42 |
| ▸ | HTR2B | P41595 | 3/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6973725 | 0.89 | HRH1 (0.47) | HRH1ADRA1ADRD2DRD3HRH3 | |
| SCHEMBL6971617 | 0.87 | HRH1 (0.44) | HRH1ADRA1AALDH1A1ADRA2ACYP2D6 | |
| Hydrochloric Acid SCHEMBL6972798 | 0.86 | LMNA (0.45) | HRH1ADRA1AALDH1A1ADRA2ACYP2D6 | |
| SCHEMBL6960271 | 0.83 | ALDH1A1 (0.42) | HRH1ADRA1AALDH1A1ADRA2ACYP2D6 | |
| SCHEMBL6964899 | 0.81 | HRH1 (0.40) | HRH1ADRA1AADRA2ADRD2ADRA2B | |
| SCHEMBL6964805 | 0.78 | LMNA (0.42) | HRH1ADRA1AALDH1A1ADRA2ACYP2D6 | |
| SCHEMBL6964808 | 0.78 | LMNA (0.42) | HRH1ADRA1AALDH1A1ADRA2ACYP2D6 | |
| SCHEMBL6963393 | 0.77 | SIGMAR1 (0.50) | HRH1ADRA1AALDH1A1ADRA2ACYP2D6 | |
| SCHEMBL6955707 | 0.77 | DRD2 (0.37) | ALDH1A1DRD2HTR2ADRD3LMNA | |
| SCHEMBL6963499 | 0.74 | HRH1 (0.49) | HRH1ADRA1ADRD3HRH3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934312-B1 | 1,4-DISUBSTITUTED PIPERAZINES | NOVO NORDISK AS (DK) | 2003-03-19 | — | — | EP | claimed |