Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | SMO | Q99835 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6961353 | 0.86 | MAPT (0.40) | LMNAMAPTHTR7ALDH1A1KDM4E | |
| SCHEMBL6961941 | 0.86 | MAPT (0.42) | LMNAMAPTHTR7ALDH1A1KDM4E | |
| SCHEMBL6966395 | 0.84 | FYN (0.43) | LMNAMAPTHTR7ALDH1A1KDM4E | |
| SCHEMBL6963927 | 0.81 | ABCG2 (0.45) | LMNAMAPTHTR7ALDH1A1GFER | |
| SCHEMBL6967175 | 0.80 | KDM4E (0.38) | LMNAMAPTALDH1A1KDM4EGFER | |
| SCHEMBL6966641 | 0.80 | TP53 (0.41) | LMNAMAPTHTR7ALDH1A1KDM4E | |
| SCHEMBL6956776 | 0.77 | MAP4K1 (0.42) | LMNAMAPTDRD4ALDH1A1KDM4E | |
| SCHEMBL6956631 | 0.77 | MAPT (0.44) | LMNAMAPTALDH1A1KDM4EGAA | |
| SCHEMBL6955333 | 0.77 | POLB (0.42) | MAPTHTR7ALDH1A1KDM4EGAA | |
| SCHEMBL6952935 | 0.75 | MAP4K1 (0.41) | HTR7ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0955293-B1 | UREA DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2003-03-19 | — | — | EP | claimed |