Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | LDHA | P00338 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | KMO | O15229 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
| ▸ | RBP4 | P02753 | 1/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.38 |
| ▸ | CTSA | P10619 | 2/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10745909 | 0.85 | LDHA (0.52) | MEN1KMT2ALDHASMN1; SMN2KDM4E | |
| SCHEMBL904650 | 0.82 | LDHA (0.46) | MEN1KMT2ALDHASMN1; SMN2KDM4E | |
| SCHEMBL11010734 | 0.82 | ALDH1A1 (0.60) | MEN1KMT2ALDHASMN1; SMN2KDM4E | |
| SCHEMBL10745184 | 0.81 | LDHA (0.49) | LDHASMN1; SMN2KDM4EALDH1A1HPGD | |
| SCHEMBL10763318 | 0.81 | LDHA (0.42) | MEN1KMT2ALDHASMN1; SMN2KDM4E | |
| SCHEMBL6954149 | 0.81 | MEN1 (0.53) | MEN1KMT2ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL6509414 | 0.81 | LMNA (0.58) | MEN1KMT2ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL2636856 | 0.79 | MEN1 (0.51) | MEN1KMT2ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL6958448 | 0.78 | SMN1; SMN2 (0.69) | MEN1KMT2ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL14941196 | 0.78 | LDHA (0.41) | MEN1KMT2ALDHASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1023267-B1 | PYRIDYL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | CERMOL SA (CH) | 2003-09-17 | — | — | EP | claimed |