Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.41 |
| ▸ | KMO | O15229 | 2/20 | 0.41 |
| ▸ | EIF4E | P06730 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | FABP3 | P05413 | 1/20 | 0.34 |
| ▸ | FABP4 | P15090 | 1/20 | 0.34 |
| ▸ | PRNP | P04156 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL904650 | 0.87 | LDHA (0.46) | LDHAALDH1A1HPGDCRHR1SMN1; SMN2 | |
| SCHEMBL6956083 | 0.78 | MEN1 (0.50) | LDHAKMOALDH1A1HPGDHSD11B1 | |
| SCHEMBL8917084 | 0.75 | LDHA (0.40) | LDHAEIF4EALDH1A1CRHR1SMN1; SMN2 | |
| SCHEMBL6956134 | 0.74 | TDP1 (0.53) | EIF4EALDH1A1MAPTTDP1L3MBTL1 | |
| SCHEMBL6956189 | 0.74 | TDP1 (0.53) | EIF4EALDH1A1MAPTTDP1L3MBTL1 | |
| SCHEMBL9280995 | 0.74 | KMT2A (0.41) | ALDH1A1MAPTTDP1L3MBTL1MEN1 | |
| SCHEMBL14472097 | 0.73 | PARP1 (0.38) | LDHAKMOEIF4EALDH1A1CRHR1 | |
| SCHEMBL28059882 | 0.73 | ALDH1A1 (0.56) | KMOALDH1A1HPGDHSD11B1MAPT | |
| SCHEMBL9281258 | 0.72 | L3MBTL1 (0.51) | ALDH1A1MAPTTDP1L3MBTL1MEN1 | |
| SCHEMBL9279745 | 0.72 | KDM4E (0.45) | EIF4EALDH1A1MAPTTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014074517-A1 | CELLULAR COMPOSITIONS USED TO RESTORE STEM CELL OR PROGENITOR CELL FUNCTION AND METHODS RELATED THERETO | EMORY UNIVERSITY (US) | 2014-05-15 | — | — | WO | claimed |
| WO-2013070852-A2 | COMPOUNDS AND COMPOSITIONS USED TO EPIGENETICALLY TRANSFORM CELLS AND METHODS RELATED THERETO | EMORY UNIVERSITY (US) | 2013-05-16 | — | — | WO | claimed |
| WO-2020167886-A1 | METHODS OF MANAGING VASCULAR CONDITIONS AND DIABETIC PERIPHERAL NEUROPATHIES | EMORY UNIVERSITY (US) | 2020-08-20 | — | — | WO | disclosed |
| WO-2014074517-A1 | CELLULAR COMPOSITIONS USED TO RESTORE STEM CELL OR PROGENITOR CELL FUNCTION AND METHODS RELATED THERETO | EMORY UNIVERSITY (US) | 2014-05-15 | — | — | WO | disclosed |