Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.30 |
| ▸ | TYMS | P04818 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6974836 | 0.90 | — | — | |
| SCHEMBL7078929 | 0.89 | TP53 (0.37) | TP53RXFP1ALOX12RAB9ASMN1; SMN2 | |
| SCHEMBL6969443 | 0.89 | DHODH (0.32) | — | |
| SCHEMBL6968860 | 0.89 | L3MBTL1 (0.33) | TP53RXFP1ALOX12GRM5MEN1 | |
| SCHEMBL6961267 | 0.88 | ALDH1A1 (0.34) | TP53RXFP1SMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL6975076 | 0.88 | TOP2A (0.31) | MEN1KMT2A | |
| SCHEMBL6973525 | 0.86 | RAB9A (0.35) | TP53RXFP1RAB9ASMN1; SMN2GRM5 | |
| SCHEMBL6972974 | 0.85 | IRAK4 (0.35) | SMN1; SMN2MEN1KMT2A | |
| SCHEMBL7085898 | 0.85 | ALDH1A1 (0.37) | TP53SMN1; SMN2KMT2A | |
| SCHEMBL7081639 | 0.85 | ALOX12 (0.38) | TP53RXFP1ALOX12RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786455-B1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO (JP) | 2003-12-03 | — | — | EP | disclosed |
| US-6147097-A | METHOD FOR TREATING AIDS | SHIONOGI & CO., LTD. (JP) | 2000-11-14 | — | — | US | disclosed |
| EP-0786455-A1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1997-07-30 | — | — | EP | disclosed |