Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 5/20 | 0.45 |
| ▸ | MAOB | P27338 | 5/20 | 0.45 |
| ▸ | ACHE | P22303 | 4/20 | 0.44 |
| ▸ | BCHE | P06276 | 3/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.41 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6956331 | 0.94 | SLC16A3 (0.46) | MAOAMAOBACHEBCHEFFAR1 | |
| SCHEMBL6960907 | 0.94 | ACHE (0.42) | MAOAMAOBACHEBCHEABCB1 | |
| SCHEMBL6952547 | 0.90 | ABCB1 (0.50) | MAOBACHEBCHEFFAR1ABCB1 | |
| SCHEMBL6956259 | 0.88 | XDH (0.48) | ABCB1XDH | |
| SCHEMBL6957097 | 0.88 | CYSLTR1 (0.41) | ACHEBCHEFFAR1ABCB1 | |
| SCHEMBL6963318 | 0.86 | CYP1A1 (0.38) | MAOAMAOBACHEBCHEFFAR1 | |
| SCHEMBL6954657 | 0.86 | SMN1; SMN2 (0.44) | ABCB1XDH | |
| SCHEMBL6960622 | 0.86 | SMN1; SMN2 (0.49) | MAOAMAOBABCB1XDH | |
| SCHEMBL6956148 | 0.85 | PTGES (0.45) | MAOAMAOBACHEBCHEABCB1 | |
| SCHEMBL6963458 | 0.85 | SMN1; SMN2 (0.46) | MAOAMAOBABCB1XDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0729465-B1 | PYRONE DERIVATIVES AS PROTEASE INHIBITORS AND ANTIVIRAL AGENTS | PARKE DAVIS & CO (US) | 2003-01-22 | — | — | EP | disclosed |
| US-6005103-A | TREATMENT OF BACTERIAL AND VIRAL INFECTIONS AND DISEASES, INCLUDING AIDS | WARNER-LAMBERT COMPANY (US) | 1999-12-21 | — | — | US | disclosed |
| US-5808062-A | AIDS THERAPY | WARNER-LAMBERT COMPANY (US) | 1998-09-15 | — | — | US | disclosed |
| EP-0729465-A1 | PYRONE DERIVATIVES AS PROTEASE INHIBITORS AND ANTIVIRAL AGENTS | PARKE, DAVIS & COMPANY (US) | 1996-09-04 | — | — | EP | disclosed |
| WO-1995014013-A1 | PYRONE DERIVATIVES AS PROTEASE INHIBITORS AND ANTIVIRAL AGENTS | PARKE, DAVIS & COMPANY (US) | 1995-05-26 | — | — | WO | disclosed |