Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.45 |
| ▸ | NPC1 | O15118 | 7/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6956617 | 0.89 | RAB9A (0.51) | RAB9ANPC1L3MBTL1SMN1; SMN2TDP1 | |
| SCHEMBL7079873 | 0.86 | REN (0.46) | RAB9ANPC1L3MBTL1SMN1; SMN2TDP1 | |
| SCHEMBL6959509 | 0.84 | NPC1 (0.44) | RAB9ANPC1L3MBTL1SMN1; SMN2 | |
| SCHEMBL6042557 | 0.82 | RAB9A (0.53) | RAB9ANPC1L3MBTL1SMN1; SMN2TDP1 | |
| SCHEMBL7076956 | 0.82 | REN (0.41) | RAB9ANPC1L3MBTL1SMN1; SMN2TDP1 | |
| SCHEMBL7082067 | 0.82 | RAB9A (0.39) | RAB9ANPC1L3MBTL1SMN1; SMN2TDP1 | |
| SCHEMBL6956029 | 0.82 | MEN1 (0.51) | RAB9ANPC1L3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL7074937 | 0.81 | MEN1 (0.41) | NPC1KMT2AMEN1 | |
| SCHEMBL7080459 | 0.81 | NPC1 (0.36) | RAB9ANPC1L3MBTL1SMN1; SMN2TDP1 | |
| SCHEMBL6954512 | 0.80 | PDE4B (0.43) | RAB9ANPC1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863875-B1 | NEW 4-(OXYALKOXYPHENYL)-3-OXY-PIPERIDINES FOR TREATING HEART AND KIDNEY INSUFFICIENCY | HOFFMANN LA ROCHE (CH) | 2003-06-04 | — | — | EP | disclosed |