Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 13/20 | 0.39 |
| ▸ | NPC1 | O15118 | 12/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7082067 | 0.91 | RAB9A (0.39) | RENRAB9ANPC1L3MBTL1SMN1; SMN2 | |
| SCHEMBL7084998 | 0.90 | REN (0.42) | RENRAB9ANPC1 | |
| SCHEMBL7073953 | 0.88 | REN (0.42) | RENSMN1; SMN2 | |
| SCHEMBL6042111 | 0.88 | REN (0.45) | RENRAB9ANPC1L3MBTL1SMN1; SMN2 | |
| SCHEMBL7076766 | 0.86 | REN (0.54) | REN | |
| SCHEMBL7079908 | 0.86 | REN (0.52) | REN | |
| SCHEMBL7080459 | 0.86 | NPC1 (0.36) | RENRAB9ANPC1L3MBTL1SMN1; SMN2 | |
| SCHEMBL7080024 | 0.85 | REN (0.41) | RENMAPTMEN1KMT2A | |
| SCHEMBL7079873 | 0.85 | REN (0.46) | RENRAB9ANPC1L3MBTL1SMN1; SMN2 | |
| SCHEMBL7082883 | 0.85 | REN (0.46) | RENL3MBTL1TDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863875-B1 | NEW 4-(OXYALKOXYPHENYL)-3-OXY-PIPERIDINES FOR TREATING HEART AND KIDNEY INSUFFICIENCY | HOFFMANN LA ROCHE (CH) | 2003-06-04 | — | — | EP | disclosed |