Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6972297 | 0.86 | ALDH1A1 (0.46) | ALDH1A1NPSR1MEN1KMT2APPARG | |
| SCHEMBL6960127 | 0.79 | NPSR1 (0.49) | ALDH1A1NPSR1MEN1KMT2APPARG | |
| SCHEMBL6972433 | 0.79 | AVPR2 (0.54) | ALDH1A1MAPT | |
| SCHEMBL6973134 | 0.78 | NPSR1 (0.47) | ALDH1A1NPSR1MEN1KMT2APPARG | |
| SCHEMBL6969459 | 0.71 | ALDH1A1 (0.46) | ALDH1A1NPSR1MEN1KMT2APPARG | |
| SCHEMBL6969797 | 0.70 | LMNA (0.44) | ALDH1A1NPSR1MEN1KMT2APPARG | |
| SCHEMBL6959586 | 0.69 | HDAC1 (0.49) | NPSR1CYP3A4 | |
| SCHEMBL6972107 | 0.69 | NOTUM (0.46) | ALDH1A1NPSR1MEN1KMT2ALMNA | |
| SCHEMBL6970661 | 0.69 | ALDH1A1 (0.46) | ALDH1A1NPSR1MEN1KMT2APPARG | |
| SCHEMBL6967260 | 0.68 | AVPR2 (0.48) | ALDH1A1MEN1KMT2ALMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620216-B1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-01-08 | — | — | EP | disclosed |
| US-5521170-A | VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0620216-A1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |