Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.49 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.40 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.40 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.37 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.37 |
| ▸ | CCKBR | P32239 | 2/20 | 0.37 |
| ▸ | XIAP | P98170 | 2/20 | 0.37 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6959376 | 0.85 | HDAC1 (0.46) | HDAC1HDAC6XIAPP2RX4 | |
| SCHEMBL6967260 | 0.77 | AVPR2 (0.48) | AVPR2AVPR1AXIAPCYP3A4 | |
| SCHEMBL6959609 | 0.77 | AVPR2 (0.50) | AVPR2AVPR1A | |
| SCHEMBL6959648 | 0.76 | AVPR1A (0.42) | HDAC1HDAC6AVPR2AVPR1AKCNN4 | |
| SCHEMBL6960127 | 0.75 | NPSR1 (0.49) | AVPR2AVPR1ACYP3A4NPSR1 | |
| SCHEMBL6970428 | 0.75 | CYP2D6 (0.43) | AVPR2AVPR1AKCNN4KCNA3NPSR1 | |
| SCHEMBL6967996 | 0.72 | AVPR2 (0.47) | AVPR2AVPR1ACYP3A4 | |
| SCHEMBL5966758 | 0.71 | CCKBR (0.48) | CCKBR | |
| SCHEMBL6958744 | 0.69 | ALDH1A1 (0.49) | CYP3A4NPSR1 | |
| SCHEMBL29286990 | 0.69 | MEN1 (0.48) | NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620216-B1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-01-08 | — | — | EP | disclosed |
| US-5521170-A | VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0620216-A1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |