Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SLC6A7 | Q99884 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TACR3 | P29371 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.38 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.38 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | MELK | Q14680 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 4/20 | 0.37 |
| ▸ | DRD4 | P21917 | 4/20 | 0.37 |
| ▸ | DRD3 | P35462 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6966648 | 0.92 | TP53 (0.41) | MEN1KMT2APOLBMAP4K1MAPT | |
| SCHEMBL6956633 | 0.89 | MAPT (0.44) | MEN1KMT2APOLBPIM1PIM3 | |
| SCHEMBL6956780 | 0.89 | MAP4K1 (0.42) | PIM1PIM3PIM2MAP4K1MELK | |
| SCHEMBL6965770 | 0.87 | MAPT (0.42) | TACR3MAP4K1ABCG2DRD2DRD4 | |
| SCHEMBL6955336 | 0.87 | POLB (0.42) | POLBTACR3MAPTHTR1A | |
| SCHEMBL6968664 | 0.86 | MAP4K1 (0.46) | MEN1KMT2APOLBMAP4K1MAPT | |
| SCHEMBL6954193 | 0.86 | ALDH1A1 (0.44) | MEN1KMT2APOLBPIM1PIM3 | |
| SCHEMBL6960415 | 0.85 | MAPT (0.46) | MEN1KMT2AMAP4K1MAPTGAA | |
| SCHEMBL6952938 | 0.84 | MAP4K1 (0.41) | TACR3MAP4K1MELKPDE3BPDE3A | |
| SCHEMBL6961535 | 0.84 | KIT (0.47) | POLBMAP4K1DRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0955293-B1 | UREA DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2003-03-19 | — | — | EP | claimed |