Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | SCD5 | Q86SK9 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | FLT3 | P36888 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6965770 | 0.83 | MAPT (0.42) | MAPTALDH1A1KDM4ELCKMAP4K3 | |
| SCHEMBL6966648 | 0.82 | TP53 (0.41) | MAPTALDH1A1LMNAHPGDNPC1 | |
| SCHEMBL6955336 | 0.81 | POLB (0.42) | MAPTALDH1A1HSD17B10NPC1RAB9A | |
| SCHEMBL6961535 | 0.81 | KIT (0.47) | MAPTALDH1A1HSD17B10LMNAHPGD | |
| SCHEMBL6956780 | 0.79 | MAP4K1 (0.42) | MAPTALDH1A1HSD17B10TSHRHPGD | |
| SCHEMBL6956633 | 0.79 | MAPT (0.44) | MAPTALDH1A1HSD17B10LMNATSHR | |
| SCHEMBL6966890 | 0.79 | KIT (0.47) | MAPTALDH1A1LMNATSHRHPGD | |
| SCHEMBL6959773 | 0.77 | KIT (0.38) | MAPTALDH1A1HSD17B10LMNAHPGD | |
| SCHEMBL6968664 | 0.77 | MAP4K1 (0.46) | MAPTALDH1A1HSD17B10LMNATSHR | |
| SCHEMBL6954193 | 0.77 | ALDH1A1 (0.44) | MAPTALDH1A1HSD17B10LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0955293-B1 | UREA DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2003-03-19 | — | — | EP | claimed |