Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | MAP4K1 | Q92918 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMO | Q99835 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6959299 | 0.92 | MEN1 (0.42) | MAP4K1MAPTMEN1KMT2ALMNA | |
| SCHEMBL6955336 | 0.88 | POLB (0.42) | TP53MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL6956633 | 0.88 | MAPT (0.44) | TP53MAP4K1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL6956780 | 0.88 | MAP4K1 (0.42) | TP53MAP4K1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL6954193 | 0.85 | ALDH1A1 (0.44) | TP53MAP4K1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL6968664 | 0.85 | MAP4K1 (0.46) | MAP4K1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL6961354 | 0.84 | CHRNA7 (0.37) | MAPTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL6965770 | 0.84 | MAPT (0.42) | MAP4K1MAPTALDH1A1SMOHTR1A | |
| SCHEMBL6961535 | 0.83 | KIT (0.47) | TP53MAP4K1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL6960766 | 0.82 | MAPT (0.35) | MAPTSMN1; SMN2MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0955293-B1 | UREA DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2003-03-19 | — | — | EP | claimed |