Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 1/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.46 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 8/20 | 0.45 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | DRD4 | P21917 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6959773 | 0.90 | KIT (0.38) | KITLCKMAP4K3MAP4K1HTR7 | |
| SCHEMBL6956633 | 0.87 | MAPT (0.44) | LCKMAP4K3MAP4K1MAPTALDH1A1 | |
| SCHEMBL6966890 | 0.86 | KIT (0.47) | KITHTR7MAPTALDH1A1HPGD | |
| SCHEMBL6966403 | 0.85 | FYN (0.43) | MAP4K1HTR7MAPTALDH1A1HPGD | |
| SCHEMBL6954193 | 0.84 | ALDH1A1 (0.44) | LCKMAP4K3MAP4K1HTR7MAPT | |
| SCHEMBL6959299 | 0.84 | MEN1 (0.42) | MAP4K1MAPTHPGDDRD2DRD4 | |
| SCHEMBL6966648 | 0.83 | TP53 (0.41) | MAP4K1MAPTALDH1A1HPGDNPSR1 | |
| SCHEMBL6955336 | 0.82 | POLB (0.42) | HTR7MAPTALDH1A1KDM4ETP53 | |
| SCHEMBL6965770 | 0.82 | MAPT (0.42) | LCKMAP4K3MAP4K1HTR7MAPT | |
| SCHEMBL6960415 | 0.81 | MAPT (0.46) | LCKMAP4K3MAP4K1MAPTSCD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0955293-B1 | UREA DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2003-03-19 | — | — | EP | claimed |