Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 9/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TACR3 | P29371 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6966648 | 0.88 | TP53 (0.41) | POLBMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL6966890 | 0.87 | KIT (0.47) | MAPTHTR7SMN1; SMN2KDM4EHTR1A | |
| SCHEMBL6952938 | 0.87 | MAP4K1 (0.41) | HTR7TACR3ALDH1A1 | |
| SCHEMBL6959299 | 0.87 | MEN1 (0.42) | POLBMAPTHTR1ATACR3 | |
| SCHEMBL6965770 | 0.83 | MAPT (0.42) | MAPTHTR7KDM4EHTR1ATACR3 | |
| SCHEMBL6961535 | 0.82 | KIT (0.47) | POLBMAPTHTR7SMN1; SMN2RAB9A | |
| SCHEMBL6961354 | 0.81 | CHRNA7 (0.37) | POLBMAPTHTR7SMN1; SMN2HTR1A | |
| SCHEMBL6960766 | 0.81 | MAPT (0.35) | POLBMAPTKCNH2SMN1; SMN2KDM4E | |
| SCHEMBL6956633 | 0.81 | MAPT (0.44) | POLBMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL6956780 | 0.81 | MAP4K1 (0.42) | MAPTSMN1; SMN2KDM4ETP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0955293-B1 | UREA DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2003-03-19 | — | — | EP | claimed |