Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.54 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.54 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.54 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.54 |
| ▸ | DHODH | Q02127 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18640758 | 0.82 | NPC1 (0.61) | KMT2AL3MBTL1DHODHGAALMNA | |
| SCHEMBL8800517 | 0.81 | KMT2A (0.67) | KMT2AL3MBTL1DHODHGAALMNA | |
| SCHEMBL7568546 | 0.80 | CHRNB2 (0.62) | KMT2AL3MBTL1CHRNB2CHRNB4CHRNA3 | |
| Toluene SCHEMBL8797778 | 0.78 | DHODH (0.56) | KMT2AL3MBTL1DHODHGAALMNA | |
| Toluene SCHEMBL8650718 | 0.78 | DHODH (0.56) | KMT2AL3MBTL1DHODHGAALMNA | |
| SCHEMBL14398931 | 0.78 | DHODH (0.56) | KMT2AL3MBTL1DHODHGAALMNA | |
| SCHEMBL31393753 | 0.78 | CHRNB2 (0.78) | KMT2AL3MBTL1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL6959593 | 0.78 | ALDH1A1 (0.53) | KMT2AL3MBTL1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL18640842 | 0.77 | KMT2A (0.64) | KMT2ADHODHGAAALDH1A1HTT | |
| SCHEMBL372 | 0.77 | KMT2A (0.60) | KMT2AGAAALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620216-B1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-01-08 | — | — | EP | disclosed |
| US-5521170-A | VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0620216-A1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |