Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | XIAP | P98170 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.40 |
| ▸ | DRD1 | P21728 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | DRD3 | P35462 | 2/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6969043 | 0.94 | DRD3 (0.47) | L3MBTL1ALDH1A1MAPTBCHEP2RX4 | |
| SCHEMBL6955542 | 0.90 | ALDH1A1 (0.43) | KDM4EL3MBTL1ALDH1A1MAPTBCHE | |
| SCHEMBL6959648 | 0.84 | AVPR1A (0.42) | ALDH1A1MAPTP2RX4HPGDHTT | |
| SCHEMBL6958687 | 0.84 | DRD3 (0.46) | L3MBTL1ALDH1A1MAPTHPGDHTT | |
| SCHEMBL6964416 | 0.81 | DRD2 (0.50) | KDM4EL3MBTL1ALDH1A1HPGDTDP1 | |
| SCHEMBL6959376 | 0.78 | HDAC1 (0.46) | L3MBTL1ALDH1A1MAPTBCHEP2RX4 | |
| SCHEMBL6970428 | 0.78 | CYP2D6 (0.43) | KDM4EALDH1A1MAPTHPGDCHRM2 | |
| SCHEMBL27431893 | 0.76 | XIAP (0.42) | L3MBTL1ALDH1A1MAPTBCHEP2RX4 | |
| SCHEMBL6970673 | 0.74 | AVPR2 (0.48) | ALDH1A1MAPTHPGDHTTCHRM2 | |
| SCHEMBL6960675 | 0.73 | AVPR2 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620216-B1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-01-08 | — | — | EP | disclosed |
| US-5521170-A | VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0620216-A1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |