Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PDCD1 | Q15116 | 5/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6955542 | 0.83 | ALDH1A1 (0.43) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL6960057 | 0.81 | PDE4A (0.43) | PDE4APDE4BPDE4CPDE4DMAPT | |
| SCHEMBL6958687 | 0.78 | DRD3 (0.46) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL6970673 | 0.77 | AVPR2 (0.48) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL6964451 | 0.76 | AVPR1A (0.49) | PDCD1CD274 | |
| SCHEMBL6955057 | 0.76 | BRD4 (0.57) | PDE4APDE4BPDE4CPDE4DMAPT | |
| SCHEMBL6968346 | 0.76 | HSD11B1 (0.41) | PDE4APDE4BPDE4CPDE4DMAPT | |
| SCHEMBL6969398 | 0.75 | ALDH1A1 (0.42) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL6970609 | 0.75 | AVPR1A (0.54) | PDCD1CD274 | |
| SCHEMBL7348149 | 0.75 | PDE4B (0.69) | PDE4APDE4BPDE4CPDE4DMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620216-B1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-01-08 | — | — | EP | disclosed |
| US-5521170-A | VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0620216-A1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |