Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | TNF | P01375 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6955924 | 0.92 | LMNA (0.47) | ALDH1A1KMT2AMEN1HPGDMGLL | |
| SCHEMBL6964263 | 0.91 | ALDH1A1 (0.42) | ALDH1A1KMT2AMEN1MGLLMAPT | |
| SCHEMBL6972651 | 0.86 | ALDH1A1 (0.41) | ALDH1A1KMT2AMEN1THRBPOLB | |
| SCHEMBL6971802 | 0.86 | SMN1; SMN2 (0.44) | ALDH1A1KMT2AMEN1MAPTPOLB | |
| SCHEMBL6966483 | 0.83 | SMN1; SMN2 (0.44) | ALDH1A1KMT2AMEN1MAPTPOLB | |
| SCHEMBL6962161 | 0.82 | LMNA (0.49) | ALDH1A1KMT2AMEN1MGLLMAPT | |
| SCHEMBL6964781 | 0.82 | L3MBTL1 (0.46) | ALDH1A1KMT2AMEN1MGLLMAPT | |
| SCHEMBL6965183 | 0.81 | ABCB1 (0.43) | ALDH1A1KMT2AMEN1MGLLMAPT | |
| SCHEMBL6964153 | 0.80 | SMN1; SMN2 (0.46) | ALDH1A1KMT2AMEN1MGLLMAPT | |
| SCHEMBL6970661 | 0.80 | ALDH1A1 (0.46) | ALDH1A1KMT2AMEN1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620216-B1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-01-08 | — | — | EP | disclosed |
| US-5521170-A | VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0620216-A1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |