Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 1/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 3/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | HTR2B | P41595 | 2/20 | 0.43 |
| ▸ | HTR3A | P46098 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | SMO | Q99835 | 1/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6956633 | 0.89 | MAPT (0.44) | SMOMAPTALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL6955336 | 0.87 | POLB (0.42) | HTR7HTR1AHTR2BHTR3AHTR2A | |
| SCHEMBL6961535 | 0.86 | KIT (0.47) | KITHTR7GSK3BMAPTALDH1A1 | |
| SCHEMBL6954193 | 0.86 | ALDH1A1 (0.44) | HTR7HTR1AHTR2BHTR3AMAPT | |
| SCHEMBL6952938 | 0.84 | MAP4K1 (0.41) | HTR7ALDH1A1HPGD | |
| SCHEMBL6959299 | 0.84 | MEN1 (0.42) | ABCG2HTR1AMAPTHPGDLMNA | |
| SCHEMBL6959773 | 0.82 | KIT (0.38) | KITHTR7MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL6966648 | 0.81 | TP53 (0.41) | HTR1ASMOMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL6965770 | 0.81 | MAPT (0.42) | ABCG2HTR7HTR1ASMOMAPT | |
| SCHEMBL6966403 | 0.81 | FYN (0.43) | CYP1A2CYP2C19HTR7HTR2BHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0955293-B1 | UREA DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2003-03-19 | — | — | EP | claimed |