Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 3/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6955604 | 0.80 | ADRA2A (0.49) | ADRA2AADRA2BADRA2CSLC6A4 | |
| SCHEMBL6949357 | 0.79 | SLC6A4 (0.56) | ADRA2AADRA2BADRA2CSLC6A4 | |
| SCHEMBL6959118 | 0.79 | SLC6A4 (0.38) | ADRA2AADRA2BADRA2CSLC6A4 | |
| SCHEMBL6950989 | 0.72 | SLC6A4 (0.45) | ADRA2AADRA2BADRA2CSLC6A4 | |
| SCHEMBL5067915 | 0.64 | — | — | |
| SCHEMBL28209626 | 0.63 | FYN (0.38) | — | |
| SCHEMBL6953435 | 0.63 | FYN (0.42) | — | |
| SCHEMBL6951255 | 0.62 | PNMT (0.38) | ADRA2AADRA2BADRA2C | |
| SCHEMBL4958734 | 0.60 | — | — | |
| SCHEMBL19506432 | 0.60 | ADRA2A (0.33) | ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1010693-B1 | Imidazoline derivatives, preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-09-24 | — | — | EP | disclosed |
| EP-1010693-A1 | Imidazoline derivatives, preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2000-06-21 | — | — | EP | disclosed |