Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 4/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6950361 | 0.89 | CYP19A1 (0.46) | ADRA2ACYP19A1 | |
| SCHEMBL6949357 | 0.82 | SLC6A4 (0.56) | ADRA2AADRA2BADRA2CSLC6A4 | |
| SCHEMBL6959118 | 0.82 | SLC6A4 (0.38) | ADRA2AADRA2BADRA2CSLC6A4 | |
| Fumaric Acid SCHEMBL8097411 | 0.79 | CYP19A1 (0.38) | ADRA2ACYP19A1 | |
| Fumaric Acid SCHEMBL8097408 | 0.79 | CYP19A1 (0.38) | ADRA2ACYP19A1 | |
| SCHEMBL6951255 | 0.73 | PNMT (0.38) | ADRA2AADRA2BADRA2C | |
| SCHEMBL6950989 | 0.71 | SLC6A4 (0.45) | ADRA2ACYP19A1ADRA2BADRA2CSLC6A4 | |
| Fumaric Acid SCHEMBL8091698 | 0.70 | ALDH1A1 (0.33) | — | |
| Fumaric Acid SCHEMBL8091705 | 0.70 | ALDH1A1 (0.33) | — | |
| SCHEMBL6960083 | 0.69 | ADRA2A (0.49) | ADRA2ACYP19A1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1183907-C | Imidazoline compound, preparing process thereof and pharmaceutical composition contg. same | SERVIER LAB (FR) | 2005-01-12 | — | — | CN | claimed |
| EP-1010693-B1 | Imidazoline derivatives, preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-09-24 | — | — | EP | claimed |
| US-6127396-A | Imidazoline compounds | ADIR ET COMPAGNIE (FR) | 2000-10-03 | — | — | US | claimed |
| CN-1257864-A | Imidazoline compound, preparing process thereof and pharmaceutical composition contg. same | ADIR (FR) | 2000-06-28 | — | — | CN | claimed |
| EP-1010693-A1 | Imidazoline derivatives, preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2000-06-21 | — | — | EP | claimed |
| CN-1183907-C | Imidazoline compound, preparing process thereof and pharmaceutical composition contg. same | SERVIER LAB (FR) | 2005-01-12 | — | — | CN | disclosed |
| EP-1010693-B1 | Imidazoline derivatives, preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-09-24 | — | — | EP | disclosed |
| US-6127396-A | Imidazoline compounds | ADIR ET COMPAGNIE (FR) | 2000-10-03 | — | — | US | disclosed |
| EP-1010693-A1 | Imidazoline derivatives, preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2000-06-21 | — | — | EP | disclosed |