Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GBA1 | P04062 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6958317 | 0.80 | CRHBP (0.40) | CRHBPCRHR2MEN1KMT2AIP6K1 | |
| SCHEMBL6960807 | 0.79 | HPGDS (0.48) | CRHBPCRHR2ALDH1A1KDM4E | |
| SCHEMBL6956099 | 0.79 | PPARG (0.52) | MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL6956100 | 0.79 | PPARG (0.52) | MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL17508122 | 0.77 | CRHBP (0.57) | CRHBPCRHR2ALDH1A1KDM4EMEN1 | |
| SCHEMBL18002715 | 0.76 | MAOA (0.46) | CRHBPCRHR2ALDH1A1KDM4EKMT2A | |
| SCHEMBL18033717 | 0.74 | PDGFRB (0.37) | ALDH1A1KDM4EPDGFRBPDGFRAMEN1 | |
| SCHEMBL24982167 | 0.74 | EGFR (0.54) | ALDH1A1KDM4EPDGFRBPDGFRAMEN1 | |
| SCHEMBL8824924 | 0.72 | MCHR1 (0.35) | CRHBPCRHR2ALDH1A1KDM4EMEN1 | |
| SCHEMBL9797715 | 0.71 | PDGFRB (0.42) | ALDH1A1KDM4EPDGFRBPDGFRAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0787725-B1 | QUINOLINE DERIVATIVE | NIPPON CHEMIPHAR CO (JP) | 2003-04-23 | — | — | EP | disclosed |
| US-5693651-A | HYPOGLYCEMIC AGENTS | NIPPON CHEMIPHAR CO., LTD. (JP) | 1997-12-02 | — | — | US | disclosed |
| EP-0787725-A1 | QUINOLINE DERIVATIVE | NIPPON CHEMIPHAR CO., LTD. (JP) | 1997-08-06 | — | — | EP | disclosed |