SCHEMBL6960808

SCHEMBL6960808

C=C(C)C1(CC(C)C)CCOC1=O

nearest known ligand 0.44

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.31
CYP2C9 P11712 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6961163 0.83 PRKCA (0.33)
SCHEMBL8593083 0.73 ALDH1A1 (0.34) LMNACYP2C9
SCHEMBL3389445 0.71 ALDH1A1 (0.36) LMNACYP2C9
SCHEMBL14037116 0.68 LMNA (0.35) LMNACYP2C9
SCHEMBL30295407 0.68 LMNA (0.35) LMNACYP2C9
SCHEMBL10442413 0.67 DPP4 (0.34) LMNACYP2C9
SCHEMBL8459306 0.67 CYP2C9 (0.32) LMNACYP2C9
SCHEMBL7563469 0.66 LMNA (0.33) LMNACYP2C9
SCHEMBL26477096 0.65 PAOX (0.34)
SCHEMBL12836369 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0898562-B1 HYDROXAMIC ACID DERIVATIVES FOR USE WITH THE TREATMENT OF DISEASES RELATED TO CONNECTIVE TISSUE DEGRADATION UPJOHN CO (US) 2003-01-22 EP disclosed
EP-0898562-A1 HYDROXAMIC ACID DERIVATIVES FOR USE WITH THE TREATMENT OF DISEASES RELATED TO CONNECTIVE TISSUE DEGRADATION PHARMACIA & UPJOHN COMPANY (US) 1999-03-03 EP disclosed
US-5712300-A ENZYME INHIBITOR PHARMACIA & UPJOHN COMPANY (US) 1998-01-27 US disclosed
WO-1997032846-A1 HYDROXAMIC ACID DERIVATIVES FOR USE WITH THE TREATMENT OF DISEASES RELATED TO CONNECTIVE TISSUE DEGRADATION PHARMACIA & UPJOHN COMPANY (US) 1997-09-12 WO disclosed