Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90B1 | P14625 | 6/20 | 0.33 |
| ▸ | TRAP1 | Q12931 | 3/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6975211 | 0.88 | LMNA (0.37) | PTGER4 | |
| SCHEMBL7084846 | 0.85 | — | — | |
| SCHEMBL6972397 | 0.84 | KCNH2 (0.34) | HSP90B1TRAP1 | |
| SCHEMBL7086413 | 0.83 | DRD2 (0.32) | — | |
| SCHEMBL7081207 | 0.82 | ALDH1A1 (0.40) | — | |
| SCHEMBL6969836 | 0.80 | HSP90B1 (0.32) | HSP90B1TRAP1HSP90AA1HSP90AB1PTGER4 | |
| SCHEMBL6972918 | 0.79 | CA2 (0.35) | PTGER4 | |
| SCHEMBL7084356 | 0.79 | HSP90B1 (0.33) | HSP90B1TRAP1HSP90AA1HSP90AB1 | |
| SCHEMBL6973233 | 0.79 | HSP90B1 (0.35) | HSP90B1TRAP1HSP90AA1HSP90AB1 | |
| SCHEMBL7084710 | 0.75 | SMN1; SMN2 (0.40) | HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786455-B1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO (JP) | 2003-12-03 | — | — | EP | disclosed |
| US-6147097-A | METHOD FOR TREATING AIDS | SHIONOGI & CO., LTD. (JP) | 2000-11-14 | — | — | US | disclosed |