Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA4 | P22748 | 2/20 | 0.35 |
| ▸ | DHODH | Q02127 | 2/20 | 0.34 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | TYMS | P04818 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | SLC6A9 | P48067 | 4/20 | 0.31 |
| ▸ | CDK4 | P11802 | 1/20 | 0.31 |
| ▸ | CCND1 | P24385 | 1/20 | 0.31 |
| ▸ | CCND2 | P30279 | 1/20 | 0.31 |
| ▸ | CCND3 | P30281 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PLK4 | O00444 | 1/20 | 0.31 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7084846 | 0.88 | — | — | |
| SCHEMBL6975211 | 0.86 | LMNA (0.37) | KMT2ATYMSALDH1A1PTGER4 | |
| SCHEMBL7081207 | 0.86 | ALDH1A1 (0.40) | KMT2AATMALDH1A1SMN1; SMN2 | |
| SCHEMBL7082707 | 0.85 | GRIN1 (0.38) | CA2CA4KMT2AATMALDH1A1 | |
| SCHEMBL7084637 | 0.85 | MAOA (0.35) | CA2CA4HAO1MAOAMAOB | |
| SCHEMBL7084710 | 0.83 | SMN1; SMN2 (0.40) | KMT2AATMALDH1A1SMN1; SMN2 | |
| SCHEMBL6968637 | 0.82 | DHODH (0.34) | CA2CA4DHODHHAO1KMT2A | |
| SCHEMBL7083636 | 0.81 | CA2 (0.36) | CA2CA4DHODHHAO1KMT2A | |
| SCHEMBL6969383 | 0.81 | DHODH (0.41) | CA2CA4DHODHHAO1KMT2A | |
| SCHEMBL6961645 | 0.79 | HSP90B1 (0.33) | PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786455-B1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO (JP) | 2003-12-03 | — | — | EP | disclosed |
| US-6147097-A | METHOD FOR TREATING AIDS | SHIONOGI & CO., LTD. (JP) | 2000-11-14 | — | — | US | disclosed |