Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CHUK | O15111 | 1/20 | 0.39 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.38 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 2/20 | 0.35 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.35 |
| ▸ | BCL6 | P41182 | 1/20 | 0.35 |
| ▸ | BCOR | Q6W2J9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6974324 | 0.84 | KMT2A (0.40) | MEN1KMT2AMAPTNPSR1TDP1 | |
| SCHEMBL6970313 | 0.84 | PGR (0.39) | MEN1KMT2AMAPTNPSR1TDP1 | |
| SCHEMBL6959978 | 0.84 | KMT2A (0.40) | MEN1KMT2AMAPTNPSR1TDP1 | |
| SCHEMBL6972315 | 0.84 | LMNA (0.46) | MEN1KMT2AMAPTNPSR1TDP1 | |
| SCHEMBL6963335 | 0.81 | LMNA (0.46) | MEN1KMT2AMAPTNPSR1TDP1 | |
| SCHEMBL6970234 | 0.81 | MAPT (0.46) | MEN1KMT2AMAPTNPSR1TDP1 | |
| SCHEMBL6971375 | 0.80 | MAPT (0.44) | MEN1KMT2AMAPTNPSR1TDP1 | |
| SCHEMBL6968103 | 0.79 | MAPT (0.48) | MEN1KMT2AMAPTNPSR1TDP1 | |
| SCHEMBL6968494 | 0.78 | ALDH1A1 (0.64) | MEN1KMT2AMAPTNPSR1TDP1 | |
| SCHEMBL8357964 | 0.78 | SLC6A2 (0.49) | MEN1KMT2AMAPTNPSR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0855391-B1 | NOVEL ISOQUINOLINE DERIVATIVES | DAIICHI SEIYAKU CO (JP) | 2003-10-15 | — | — | EP | disclosed |
| US-5959107-A | Isoquinoline derivatives | SNOW BRAND MILK PRODUCTS CO., LTD. (JP) | 1999-09-28 | — | — | US | disclosed |
| EP-0855391-A1 | NOVEL ISOQUINOLINE DERIVATIVES | SNOW BRAND MILK PRODUCTS CO., LTD. (JP) | 1998-07-29 | — | — | EP | disclosed |