Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 4/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CHUK | O15111 | 1/20 | 0.36 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.35 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6961855 | 0.84 | MEN1 (0.41) | PDE3BPDE3AKMT2AMEN1MAPT | |
| SCHEMBL6959978 | 0.80 | KMT2A (0.40) | PDE3BPDE3AKMT2AMEN1MAPT | |
| SCHEMBL6963394 | 0.79 | PGR (0.39) | PGRPDE3BPDE3AMAPTTDP1 | |
| SCHEMBL6974578 | 0.79 | HTT (0.41) | KMT2AMEN1MAPTNPSR1TDP1 | |
| SCHEMBL6974324 | 0.78 | KMT2A (0.40) | PDE3BPDE3AKMT2AMEN1MAPT | |
| SCHEMBL6963335 | 0.77 | LMNA (0.46) | KMT2AMEN1MAPTNPSR1TDP1 | |
| SCHEMBL6972315 | 0.77 | LMNA (0.46) | KMT2AMEN1MAPTNPSR1TDP1 | |
| SCHEMBL6970234 | 0.76 | MAPT (0.46) | KMT2AMEN1MAPTNPSR1TDP1 | |
| SCHEMBL6971375 | 0.76 | MAPT (0.44) | KMT2AMEN1MAPTNPSR1TDP1 | |
| SCHEMBL6968103 | 0.75 | MAPT (0.48) | KMT2AMEN1MAPTNPSR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0855391-B1 | NOVEL ISOQUINOLINE DERIVATIVES | DAIICHI SEIYAKU CO (JP) | 2003-10-15 | — | — | EP | disclosed |
| EP-0855391-A1 | NOVEL ISOQUINOLINE DERIVATIVES | SNOW BRAND MILK PRODUCTS CO., LTD. (JP) | 1998-07-29 | — | — | EP | disclosed |