Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 10/20 | 0.38 |
| ▸ | PPARG | P37231 | 8/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.34 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7137764 | 0.94 | BRD4 (0.40) | BRD4PPARAPPARGPDE3BPDE3A | |
| SCHEMBL6957796 | 0.91 | MAPT (0.35) | PPARAPPARGTP53MAPTKMT2A | |
| SCHEMBL6962244 | 0.88 | KMT2A (0.35) | PPARAPPARGTP53MAPTKMT2A | |
| SCHEMBL6956604 | 0.86 | KMT2A (0.35) | PPARAPPARGTP53MAPTKMT2A | |
| SCHEMBL6958365 | 0.85 | MAPT (0.38) | PPARAPPARGTP53MAPTKMT2A | |
| SCHEMBL6955926 | 0.85 | P2RX3 (0.34) | TP53MAPTKMT2A | |
| SCHEMBL6965486 | 0.84 | KMT2A (0.37) | BRD4PPARAPPARGTP53MAPT | |
| SCHEMBL6962957 | 0.83 | KMT2A (0.35) | BRD4PPARAPPARGTP53MAPT | |
| SCHEMBL6958019 | 0.83 | FKBP1A (0.33) | PPARAPPARGTP53MAPTKMT2A | |
| SCHEMBL6963612 | 0.82 | KMT2A (0.35) | TP53MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015444-B1 | PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP LTD (KR) | 2003-05-28 | — | — | EP | claimed |