Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.57 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | PSMB1 | P20618 | 3/20 | 0.48 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.48 |
| ▸ | PSMB2 | P49721 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7443798 | 0.81 | PSMB1 (0.50) | LTA4HHRH3KDM4EPSMB1PSMB5 | |
| SCHEMBL7445444 | 0.80 | PSMB1 (0.44) | LTA4HHRH3KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL14970714 | 0.79 | HRH3 (0.76) | LTA4HHRH3KDM4EALDH1A1KMT2A | |
| SCHEMBL15474805 | 0.79 | HRH3 (0.76) | LTA4HHRH3KDM4EALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL14966772 | 0.78 | HRH3 (0.74) | LTA4HHRH3KDM4EALDH1A1KMT2A | |
| SCHEMBL14970684 | 0.78 | LTA4H (0.82) | LTA4HHRH3KDM4EPOLBPSMB1 | |
| SCHEMBL15257179 | 0.78 | LTA4H (0.82) | LTA4HHRH3KDM4EPOLBPSMB1 | |
| SCHEMBL6957435 | 0.78 | LTA4H (0.76) | LTA4HHRH3KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL27081892 | 0.77 | LTA4H (0.59) | LTA4HHRH3KDM4EALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL14966283 | 0.77 | LTA4H (0.79) | LTA4HHRH3KDM4EPOLBPSMB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0980367-A4 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2003-03-19 | — | — | EP | disclosed |
| EP-0980367-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2000-02-23 | — | — | EP | disclosed |
| EP-0863755-A4 | ANTITHROMBOTIC DIAMINES | LILLY CO ELI (US) | 1999-01-20 | — | — | EP | disclosed |
| WO-1998049161-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1998-11-05 | — | — | WO | disclosed |
| EP-0863755-A1 | ANTITHROMBOTIC DIAMINES | ELI LILLY AND COMPANY (US) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997025033-A1 | ANTITHROMBOTIC DIAMINES | ELI LILLY AND COMPANY (US) | 1997-07-17 | — | — | WO | disclosed |