Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB1 | P20618 | 5/20 | 0.50 |
| ▸ | PSMB5 | P28074 | 5/20 | 0.50 |
| ▸ | PSMB2 | P49721 | 5/20 | 0.50 |
| ▸ | ESR1 | P03372 | 6/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 4/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6962494 | 0.81 | LTA4H (0.57) | PSMB1PSMB5PSMB2KDM4ELTA4H | |
| SCHEMBL6957435 | 0.78 | LTA4H (0.76) | KDM4ELTA4HHRH3 | |
| SCHEMBL27081892 | 0.77 | LTA4H (0.59) | PSMB1PSMB5PSMB2KDM4ELTA4H | |
| SCHEMBL7445444 | 0.77 | PSMB1 (0.44) | PSMB1PSMB5PSMB2KDM4ELTA4H | |
| SCHEMBL2475993 | 0.76 | ESR1 (0.75) | PSMB1PSMB5PSMB2ESR1ESR2 | |
| SCHEMBL1359959 | 0.75 | ESR1 (0.76) | PSMB1PSMB5PSMB2ESR1ESR2 | |
| SCHEMBL699174 | 0.75 | ESR1 (0.76) | PSMB1PSMB5PSMB2ESR1ESR2 | |
| SCHEMBL1282982 | 0.74 | LTA4H (0.58) | PSMB1PSMB5PSMB2KDM4ELTA4H | |
| SCHEMBL7777295 | 0.74 | LTA4H (0.53) | PSMB1PSMB5PSMB2ESR1ESR2 | |
| SCHEMBL7444923 | 0.73 | SLC6A3 (0.46) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863755-A4 | ANTITHROMBOTIC DIAMINES | LILLY CO ELI (US) | 1999-01-20 | — | — | EP | disclosed |
| EP-0863755-A1 | ANTITHROMBOTIC DIAMINES | ELI LILLY AND COMPANY (US) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997025033-A1 | ANTITHROMBOTIC DIAMINES | ELI LILLY AND COMPANY (US) | 1997-07-17 | — | — | WO | disclosed |