Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 8/20 | 0.76 |
| ▸ | HTT | P42858 | 2/20 | 0.67 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.60 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | NPY1R | P25929 | 1/20 | 0.56 |
| ▸ | BACE1 | P56817 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2476820 | 0.87 | LTA4H (1.00) | LTA4HHTTKCNH2MCHR1KDM4E | |
| SCHEMBL4688871 | 0.85 | LTA4H (0.97) | LTA4HHTTKCNH2MCHR1KDM4E | |
| SCHEMBL20748052 | 0.85 | LTA4H (0.97) | LTA4HHTTKCNH2MCHR1KDM4E | |
| SCHEMBL3065928 | 0.80 | MAOB (0.58) | RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL4689454 | 0.80 | KDM4E (0.86) | LTA4HHTTKCNH2KDM4ENPC1 | |
| SCHEMBL14970586 | 0.78 | NPC1 (0.87) | LTA4HHTTKCNH2KDM4ENPC1 | |
| SCHEMBL3581020 | 0.78 | NPC1 (0.87) | LTA4HHTTKCNH2KDM4ENPC1 | |
| SCHEMBL6960875 | 0.78 | LTA4H (0.78) | LTA4HHTTKCNH2MCHR1KDM4E | |
| SCHEMBL6962494 | 0.78 | LTA4H (0.57) | LTA4HKDM4ESMN1; SMN2HRH3ALDH1A1 | |
| SCHEMBL7443798 | 0.78 | PSMB1 (0.50) | LTA4HKDM4EHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0980367-A4 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2003-03-19 | — | — | EP | disclosed |
| EP-0980367-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2000-02-23 | — | — | EP | disclosed |
| EP-0863755-A4 | ANTITHROMBOTIC DIAMINES | LILLY CO ELI (US) | 1999-01-20 | — | — | EP | disclosed |
| WO-1998049161-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1998-11-05 | — | — | WO | disclosed |
| EP-0863755-A1 | ANTITHROMBOTIC DIAMINES | ELI LILLY AND COMPANY (US) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997025033-A1 | ANTITHROMBOTIC DIAMINES | ELI LILLY AND COMPANY (US) | 1997-07-17 | — | — | WO | disclosed |