Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6975922 | 0.85 | NPC1 (0.43) | MEN1KMT2AHPGDMAPTALDH1A1 | |
| SCHEMBL6970855 | 0.85 | KCNA5 (0.53) | MEN1KMT2AMAPTALDH1A1TSHR | |
| SCHEMBL6969751 | 0.84 | SGMS1 (0.47) | KMT2AALDH1A1CYP2C19TP53LMNA | |
| SCHEMBL6977607 | 0.84 | KCNH2 (0.40) | MEN1KMT2AMAPTALDH1A1TSHR | |
| SCHEMBL6975974 | 0.81 | AKR1C3 (0.48) | MEN1KMT2AMAPTKDM4ECYP2C9 | |
| SCHEMBL6972542 | 0.80 | MAPT (0.47) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL6967437 | 0.79 | KMT2A (0.43) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL6976503 | 0.79 | MAPT (0.41) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL6977877 | 0.78 | HTR6 (0.46) | MEN1KMT2AHPGDMAPTALDH1A1 | |
| SCHEMBL6962516 | 0.78 | MAPT (0.45) | MEN1KMT2AMAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077947-B1 | NOVEL 1,5 AND 3-O-SUBSTITUTED 1H-INDAZOLES WITH ANTI-ASTHMATIC, ANTI-ALLERGIC, ANTI-INFLAMMATORY, IMMUNO-MODULATING AND NEURO-PROTECTIVE EFFECT, METHOD FOR THE PRODUCTION AND USE THEREOF AS MEDICAMENTS | DRESDEN ARZNEIMITTEL (DE) | 2003-09-03 | — | — | EP | claimed |