Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL268150 | 0.76 | MEN1 (0.68) | PDE7AALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL6963075 | 0.75 | HSD17B10 (0.42) | ALDH1A1LMNAMEN1KMT2AMAPT | |
| Diphenylsulfane SCHEMBL27732156 | 0.70 | MEN1 (0.55) | PDE7AALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL9710324 | 0.70 | ALDH1A1 (0.48) | ALDH1A1LMNAMEN1KMT2AMAPT | |
| Phosphonic Acid SCHEMBL11661426 | 0.69 | MEN1 (0.58) | PDE7AALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL10706021 | 0.69 | TSHR (0.42) | ALDH1A1LMNAMAPTL3MBTL1ATM | |
| SCHEMBL8729226 | 0.69 | ALDH1A1 (0.62) | PDE7AALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL2887765 | 0.68 | HSP90AA1 (0.69) | PDE7AALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL4163474 | 0.67 | MAPT (0.79) | PDE7AALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL3328543 | 0.67 | MAPT (0.79) | PDE7AALDH1A1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |
| EP-0240680-A1 | Diaryl sulfide derivatives | BAYER AG (DE) | 1987-10-14 | — | — | EP | disclosed |