Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | TAS2R14 | Q9NYV8 | 4/20 | 0.52 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11469731 | 0.77 | KDM4E (0.51) | ALDH1A1LMNAKDM4EHSD17B10TAS2R14 | |
| SCHEMBL14470257 | 0.76 | ALDH1A1 (0.69) | ALDH1A1LMNAKDM4ETAS2R14TP53 | |
| SCHEMBL31612502 | 0.74 | MAPT (0.63) | ALDH1A1LMNATAS2R14HTTSMN1; SMN2 | |
| SCHEMBL6964287 | 0.73 | BCHE (0.59) | LMNAHSD17B10PTGER1POLBSMN1; SMN2 | |
| SCHEMBL9302981 | 0.73 | NR1H3 (0.61) | ALDH1A1LMNATAS2R14HTTTSHR | |
| SCHEMBL29966020 | 0.73 | LMNA (0.63) | ALDH1A1LMNATAS2R14TP53HTT | |
| SCHEMBL6324075 | 0.72 | KEAP1 (0.53) | ALDH1A1LMNAKDM4ETAS2R14HTT | |
| SCHEMBL11441279 | 0.72 | C5AR1 (0.67) | ALDH1A1LMNAHTTPOLBC5AR1 | |
| SCHEMBL6964289 | 0.72 | SMN1; SMN2 (0.46) | ALDH1A1LMNAKDM4EHSD17B10PTGER1 | |
| SCHEMBL9316876 | 0.72 | CA12 (0.47) | KDM4EHSD17B10PTGER1POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113277963-B | Amine compound and preparation method and application thereof | 南京工业大学 | 2022-11-04 | — | — | CN | disclosed |