Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.55 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | IDO1 | P14902 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29094950 | 0.85 | MAPT (0.50) | MAPTKDM4ENPC1RAB9AHSD17B10 | |
| SCHEMBL11398581 | 0.81 | GAA (0.63) | KDM4ENPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL400890 | 0.81 | RAB9A (0.77) | KDM4ENPC1RAB9APTGS2CTDSP1 | |
| SCHEMBL6966527 | 0.81 | MAPT (0.59) | MAPTKDM4ENPC1RAB9APTGS2 | |
| SCHEMBL28003152 | 0.81 | MAPT (0.59) | MAPTKDM4ENPC1RAB9APTGS2 | |
| SCHEMBL3003252 | 0.79 | ALDH1A1 (0.69) | KDM4EPTGS2HDAC3CA1HDAC1 | |
| SCHEMBL18745918 | 0.79 | TPMT (0.45) | MAPTKDM4ENPC1RAB9ACTDSP1 | |
| SCHEMBL8681380 | 0.79 | ALDH1A1 (0.57) | MAPTKDM4ENPC1RAB9ACTDSP1 | |
| SCHEMBL16312774 | 0.79 | LMNA (0.52) | MAPTKDM4ENPC1RAB9ACA12 | |
| SCHEMBL12324391 | 0.79 | RAB9A (0.82) | MAPTKDM4ENPC1RAB9APTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1230196-A | Modified aminoacids, pharmaceuticals containing these compounds and method for their prodn. | THOMAE GMBH DR K (DE) | 1999-09-29 | — | — | CN | claimed |
| WO-2023107557-A1 | COMPOUNDS AND COMPOSITIONS THAT INHIBIT PIKFYVE | Kineta, Inc. (US) | 2023-06-15 | — | — | WO | disclosed |
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |
| US-5110986-A | Reaction of a 1,3,4-oxadiazole with a tert-alkyl cation precursor in presence of strong acid catalyst | ROHM AND HAAS COMPANY (US) | 1992-05-05 | — | — | US | disclosed |