Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6964298 | 0.81 | MAPT (0.61) | MAPTKDM4ENPC1RAB9ACTDSP1 | |
| SCHEMBL400890 | 0.79 | RAB9A (0.77) | KDM4ENPC1RAB9ACTDSP1PTGS2 | |
| SCHEMBL28003152 | 0.79 | MAPT (0.59) | MAPTKDM4ENPC1RAB9ACTDSP1 | |
| SCHEMBL3247733 | 0.78 | NPC1 (0.57) | MAPTKDM4ENPC1RAB9ACTDSP1 | |
| SCHEMBL12324391 | 0.77 | RAB9A (0.82) | MAPTKDM4ENPC1RAB9ACTDSP1 | |
| SCHEMBL28004151 | 0.76 | NPC1 (0.70) | MAPTKDM4ENPC1RAB9ACTDSP1 | |
| SCHEMBL16438824 | 0.75 | HDAC3 (0.68) | MAPTKDM4ENPC1RAB9ACTDSP1 | |
| SCHEMBL11298577 | 0.74 | RAB9A (0.75) | KDM4ENPC1RAB9ACTDSP1ALDH1A1 | |
| SCHEMBL6967578 | 0.74 | RAB9A (0.63) | KDM4ENPC1RAB9ACTDSP1PTGS2 | |
| SCHEMBL28875360 | 0.73 | SMN1; SMN2 (0.71) | KDM4ENPC1RAB9ACTDSP1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |