Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.39 |
| ▸ | CDK4 | P11802 | 2/20 | 0.39 |
| ▸ | CCND1 | P24385 | 2/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.39 |
| ▸ | CDK2 | P24941 | 2/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.38 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6974758 | 0.87 | DRD2 (0.36) | MAPTALDH1A1LMNANPC1RAB9A | |
| SCHEMBL6956631 | 0.84 | MAPT (0.44) | MAPTALDH1A1TSHRKDM4EHPGD | |
| SCHEMBL6960082 | 0.82 | MAPT (0.47) | MAPTALDH1A1KDM4EHPGDCCNE2 | |
| SCHEMBL6973060 | 0.82 | MAPT (0.38) | MAPTALDH1A1LMNATP53HTR1A | |
| SCHEMBL6964321 | 0.78 | MAPT (0.40) | MAPTALDH1A1TSHRKDM4EHPGD | |
| SCHEMBL6955871 | 0.77 | MAPT (0.40) | MAPTALDH1A1TSHRKDM4EHPGD | |
| SCHEMBL6966887 | 0.73 | KIT (0.47) | MAPTALDH1A1TSHRKDM4EHPGD | |
| SCHEMBL6968659 | 0.73 | MAP4K1 (0.46) | MAPTALDH1A1TSHRKDM4EHPGD | |
| SCHEMBL6959295 | 0.72 | MEN1 (0.42) | MAPTALDH1A1HPGDPIM1PIM3 | |
| SCHEMBL6966641 | 0.72 | TP53 (0.41) | MAPTALDH1A1KDM4EHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0945439-B1 | AMINOPYRAZOLE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2003-03-19 | — | — | EP | claimed |