Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.41 |
| ▸ | CDK4 | P11802 | 2/20 | 0.41 |
| ▸ | CCND1 | P24385 | 2/20 | 0.41 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.41 |
| ▸ | CDK2 | P24941 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.38 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6956631 | 0.86 | MAPT (0.44) | MAPTALDH1A1RAB9ANPC1CCNE2 | |
| SCHEMBL6964319 | 0.82 | MAPT (0.40) | MAPTALDH1A1RAB9ANPC1CCNE2 | |
| SCHEMBL6960085 | 0.78 | MAPT (0.47) | MAPTALDH1A1RAB9ANPC1HSD11B1 | |
| SCHEMBL6955871 | 0.77 | MAPT (0.40) | MAPTALDH1A1RAB9ANPC1HSD11B1 | |
| SCHEMBL6968659 | 0.75 | MAP4K1 (0.46) | MAPTALDH1A1HTTSMN1; SMN2LMNA | |
| SCHEMBL6959295 | 0.74 | MEN1 (0.42) | MAPTALDH1A1SMN1; SMN2LMNAHPGD | |
| SCHEMBL6961528 | 0.73 | HTR7 (0.48) | MAPTALDH1A1RAB9ALMNAHPGD | |
| SCHEMBL6967175 | 0.72 | KDM4E (0.38) | MAPTALDH1A1SMN1; SMN2LMNAHPGD | |
| SCHEMBL6956776 | 0.71 | MAP4K1 (0.42) | MAPTALDH1A1CCNE2CDK4CCND1 | |
| SCHEMBL6974758 | 0.69 | DRD2 (0.36) | MAPTALDH1A1RAB9ANPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0955293-B1 | UREA DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2003-03-19 | — | — | EP | claimed |