Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.34 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 3/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.33 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.33 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | IKBKB | O14920 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | ARF6 | P62330 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6974758 | 0.89 | DRD2 (0.36) | MAPTALDH1A1LCATLMNA | |
| SCHEMBL6961941 | 0.84 | MAPT (0.42) | MAPTHTR1AHTR7PPP1CABCL2A1 | |
| SCHEMBL6964319 | 0.82 | MAPT (0.40) | MAPTHTR1AHTR7ALDH1A1LMNA | |
| SCHEMBL6977630 | 0.78 | MAPT (0.38) | MAPTHTR1AHTR7PPP1CABCL2A1 | |
| SCHEMBL6963927 | 0.71 | ABCG2 (0.45) | MAPTHTR1AHTR7ALDH1A1SIGMAR1 | |
| SCHEMBL6959295 | 0.70 | MEN1 (0.42) | MAPTHTR1AALDH1A1PDE3BPDE3A | |
| SCHEMBL6955903 | 0.70 | LMNA (0.41) | MAPTHTR7ALDH1A1LMNA | |
| SCHEMBL6966641 | 0.68 | TP53 (0.41) | MAPTHTR1AHTR7ALDH1A1LMNA | |
| SCHEMBL6967175 | 0.68 | KDM4E (0.38) | MAPTALDH1A1PDE3BPDE3ALMNA | |
| SCHEMBL6966146 | 0.67 | ABCG2 (0.43) | MAPTHTR7ALDH1A1PDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0945439-B1 | AMINOPYRAZOLE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2003-03-19 | — | — | EP | claimed |