Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.36 |
| ▸ | DRD4 | P21917 | 7/20 | 0.36 |
| ▸ | DRD3 | P35462 | 6/20 | 0.36 |
| ▸ | MAPK13 | O15264 | 3/20 | 0.36 |
| ▸ | MAPK12 | P53778 | 3/20 | 0.36 |
| ▸ | MAPK11 | Q15759 | 3/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LCAT | P04180 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6973060 | 0.89 | MAPT (0.38) | MAPTLMNAALDH1A1LCAT | |
| SCHEMBL6964319 | 0.87 | MAPT (0.40) | MAPTLMNAALDH1A1RAB9ANPC1 | |
| SCHEMBL6974762 | 0.77 | LCAT (0.37) | DRD2DRD4DRD3MAPK13MAPK12 | |
| SCHEMBL8308786 | 0.76 | DRD4 (0.43) | DRD2DRD4DRD3MAPK13MAPK12 | |
| SCHEMBL6959295 | 0.74 | MEN1 (0.42) | DRD2DRD4DRD3MAPTLMNA | |
| SCHEMBL8143341 | 0.72 | LMNA (0.38) | DRD3MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL6966641 | 0.72 | TP53 (0.41) | MAPTLMNAALDH1A1RAB9ANPC1 | |
| SCHEMBL6967175 | 0.72 | KDM4E (0.38) | DRD2DRD3MAPTLMNAALDH1A1 | |
| SCHEMBL6963927 | 0.72 | ABCG2 (0.45) | MAPTLMNAALDH1A1KMT2A | |
| SCHEMBL6961941 | 0.72 | MAPT (0.42) | MAPTLMNAALDH1A1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0945439-B1 | AMINOPYRAZOLE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2003-03-19 | — | — | EP | claimed |
| EP-0945439-B1 | AMINOPYRAZOLE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2003-03-19 | — | — | EP | disclosed |
| US-6166038-A | Aminopyrazole derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-12-26 | — | — | US | disclosed |
| EP-0945439-A1 | NOVEL AMINOPYRAZOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-09-29 | — | — | EP | disclosed |